CHEST Board Review: SEEK Sessions (4 New Videos! October 2025)-SEEK Board Review Session 2025: Dr. Stephanie Levine

Video Transcription

Video Summary

The transcript discusses several pulmonary cases and diseases. First, lymphangioleiomyomatosis (LAM) is a rare premenopausal disease characterized by cystic lung changes, chylothorax, and positive HMB45 staining; treatment includes rapamycin, and disease can recur post-lung transplant. Comparisons with pulmonary Langerhans cell histiocytosis (PLCH) highlight different demographics and imaging features. The next case involves actinomycosis, a chronic pneumonia-like infection caused by anaerobic bacteria requiring prolonged penicillin treatment. Then, a mediastinal mass in a woman is identified as thymoma, often linked with paraneoplastic syndromes such as myasthenia gravis and pure red cell aplasia; resection is typically recommended. Sarcoidosis is noted as the most common disease to recur after lung transplantation. Finally, a solitary fibrous tumor of the pleura is explained, presenting with isolated pleural masses, possible paraneoplastic hypoglycemia, and clubbing. Imaging features and treatment approaches are emphasized to aid differential diagnosis and management.

Keywords

lymphangioleiomyomatosis

pulmonary langerhans cell histiocytosis

actinomycosis

thymoma

sarcoidosis