CHEST Guidelines-Association-Between-Compliance-With-the-Sepsis-Qua

Association-Between-Compliance-With-the-Sepsis-Qua

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The recent study evaluated the relationship between adherence to the Sepsis Quality Measure (SEP-1) and hospital readmissions after surviving sepsis. It found that compliance with SEP-1, which is a bundled care treatment strategy, was associated with more favorable patient outcomes. Specifically, hospitals that adhered to SEP-1 were linked to reduced mortality rates, more frequent discharges to home, and fewer incidences of readmission within 30 days. The SEP-1 compliance was also linked to a shorter length of stay in hospitals.<br /><br />The study analyzed data from the Cleveland Clinic Health System, involving adult patients hospitalized for sepsis between October 2015 and March 2019. A subset of 3,799 first-encounter cases was examined for SEP-1 compliance. The study employed multivariable logistic regression models to control for factors like age, sex, race, hospital specifics, and comorbidity indices, finding significant results supporting the benefits of SEP-1 compliance.<br /><br />Within the 3,443 patients who survived their hospitalization, those compliant with SEP-1 saw a lower 30-day readmission rate (18.5%) compared to the non-compliant group (22.7%). The association between SEP-1 compliance and reduced mortality was notable especially when septic shock was not present, suggesting that adherence to SEP-1 may improve patients' functional status and allow for more effective discharge practices. However, when septic shock was present, no significant mortality association was found.<br /><br />Despite these positive associations, the study also noted challenges with the administrative complexity and rigidity of SEP-1, particularly when dealing with septic shock, which requires more components to be met. The study emphasized the importance of timely antibiotic administration as a critical factor in the success of SEP-1 compliance. This study builds upon previous research and presents SEP-1 compliance as a modifiable risk factor that could decrease readmissions and improve patient outcomes in sepsis care.

Keywords

Sepsis Quality Measure

SEP-1 compliance

hospital readmissions

mortality rates

Cleveland Clinic Health System

multivariable logistic regression

30-day readmission rate

septic shock

antibiotic administration

sepsis care