CHEST Guidelines-Giants-in-Chest-Medicine

Giants-in-Chest-Medicine_chest

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Leonardo M. Fabbri, MD, is a leading figure in respiratory medicine, known for his pioneering work in asthma and chronic obstructive pulmonary disease (COPD). He holds prestigious positions at the University of Modena and Reggio Emilia in Italy, where he has significantly advanced the understanding and management of respiratory diseases. Dr. Fabbri's academic path began with a Doctorate in Medicine from the University of Padua in 1972, progressing through occupational and respiratory medicine. His international experience includes significant research collaborations in the United States at Tulane University and the Cardiovascular Research Institute at the University of California.<br /><br />Dr. Fabbri's early research focused on the epidemiology of occupational lung diseases, with a seminal focus on occupational asthma induced by substances like isocyanates. His studies illuminated the relationship between airway hyperresponsiveness and inflammation. Through crucial research at the Cardiovascular Research Institute, he demonstrated the significant role that neutrophilic inflammation plays in ozone-induced airway hyperresponsiveness in dogs, work that was later validated in human subjects.<br /><br />Over his expansive career, Dr. Fabbri has integrated experimental research insights into clinical practice, contributing significantly to guidelines for asthma and COPD management under initiatives such as GINA and GOLD. His work encompasses landmark trials on the efficacy of inhaled steroids, bronchodilators, and combination therapies for these conditions. Recently, Dr. Fabbri has focused on the intersection between COPD and broader chronic multimorbidities, recognizing this as a crucial health challenge.<br /><br />As President of the European Respiratory Society, he emphasized the need for interdisciplinary collaboration across medical fields to address these complex health issues. His research, guidance, and leadership continue to influence respiratory medicine globally, providing critical insights into airway diseases and paving the way for future advancements.

Keywords

Leonardo M. Fabbri

respiratory medicine

asthma

COPD

University of Modena

neutrophilic inflammation

GINA

GOLD

European Respiratory Society

chronic multimorbidities