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CHEST Guidelines
VTE-Risk-Profiles-and-Prophylaxis-in-Medical-and-S
VTE-Risk-Profiles-and-Prophylaxis-in-Medical-and-S
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Pdf Summary
The study, "Identification of Chinese Hospitalized Patients’ Risk Profile for Venous Thromboembolism (DissolVE-2)," explores VTE risk and prophylaxis among Chinese inpatients. Conducted in 60 urban hospitals from March to September 2016, it involved 13,609 patients (6,986 surgical and 6,623 medical). VTE risk was assessed using the Padua Prediction Score and Caprini Risk Assessment model, following the 9th edition of the American College of Chest Physicians (CHEST) guidelines.<br /><br />The study revealed that 53.4% of surgical patients and 36.6% of medical patients were at high risk for VTE. The major risk factors for surgical patients were major open surgery (52.6%), while acute infection posed the greatest risk for medical patients (42.2%). Despite the significant risk, the overall rate of any VTE prophylaxis was just 14.3%, with appropriate prophylactic measures administered to only 10.3% of patients—19% in surgical and 9.3% in medical settings.<br /><br />The results emphasize suboptimal implementation of VTE prevention correlating to western-based guidelines, with just one-third of appropriate prophylaxis being administered. Geographically, prophylaxis administration varied, revealing a disparity in VTE preventive measures across regions.<br /><br />The study highlights the gap between guideline recommendations and actual clinical practice in China, indicating a need for increased awareness and improved VTE risk management among Chinese healthcare providers. These findings could inform necessary enhancements in medical education and clinical practices to better align with international standards and tackle the growing VTE burden in the Chinese healthcare system. The study was supported by Sanofi and the National Key Research and Development Program of China.
Keywords
Venous Thromboembolism
Chinese inpatients
VTE risk
prophylaxis
Padua Prediction Score
Caprini Risk Assessment
CHEST guidelines
surgical patients
medical patients
clinical practice
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